Nootropic stacks are an important part of any biohackers regimen. The idea is to use a combination of nootropics to deliver the best results possible.
The simplest way to get into nootropics is to purchase premade nootropic stacks like Alpha brain. As you become more familiar with nootropics and how they work, it’s recommended that you begin creating your own nootropic stacks. This allows you to control the dose and “dial it in” perfectly to your own body. Custom stacking is also much cheaper than premade stack because you can simply buy the raw materials in bulk rather than marked up premade formulas.
We prepared a nootropic stack guide for you to answer all popular questions about nootropics.

What Are Nootropics Stacks?
A nootropic stack, basically, is the blend of at least two supplements that affect memory, learning, center, or inspiration, with a specific end goal to make a synergistic impact in the cerebrum more noteworthy than any expansion in cognizance than the supplements you “stack” could make alone. It’s a supplementation procedure that numerous nootropic clients exploit to support the capacities of their cerebrum more distant than any single supplement could do alone. There are 2 ways to begin with nootropics stacks:
One alternative is to just purchase a preformulated stack from a supplement producer that has made their own mix of nootropics into case shape.
These “off the rack” nootropics have the advantage of being ensured to work to some degree and offer accommodation over weighing out and blending your own nootropic mixes.
In any case, these preformulated stacks are incredible in case you’re searching for a helpful “prepared to go” prologue to nootropics that can be gone up against their own particular or utilized as a construct which can be extended in light of by taking them with different nootropics, for example, a racetam.
Ensure you stick to respectable organizations while picking a preformulated nootropic. This is the reason Mind Lab Pro is our preformulated nootropic heap of the decision as it is created by a respectable organization and their mix has been magnificently made.
Custom Stack
One alternative is to just purchase a preformulated stack from a supplement producer that has made their own mix of nootropics into case shape.
These “off the rack” nootropics have the advantage of being ensured to work to some degree and offer accommodation over weighing out and blending your own nootropic mixes.
In any case, these preformulated stacks are incredible in case you’re searching for a helpful “prepared to go” prologue to nootropics that can be gone up against their own particular or utilized as a construct which can be extended in light of by taking them with different nootropics, for example, a racetam.
Ensure you stick to respectable organizations while picking a preformulated nootropic. This is the reason Mind Lab Pro is our preformulated nootropic heap of the decision as it is created by a respectable organization and their mix has been magnificently made.
Perfect Nootropic Stack For Mental Health and Stability
- Pramiracetam: improves cognition and motor coordination by increasing acetylcholine receptors in your brain
- Turmeric (Curcumin): has plenty of benefits including improving immune system, calming effects, brain recovery and others. Find out more about this herbal nootropic in our post.
- Omega 3 fatty acids: is an essential component for building cells, neurons and synapses.
- Anasthaxin Oil: helps to protect neurons and improves cells recovery. It results in raising attention, improvement of reaction time
- Vitamin D3 is produced in out body when we are sun-bathing. It’s well-known for its anti-aging effects, diabetes cure, improving immune system and other benefits.
Perfect Nootropic Stack For Creativity and Improvisation
- Sublitamine: being a synthetic analogue of vitamin B1, it improves blood circulation, improving memory, concentration and decision making.
- Phenylpiracetam, piracetam and aniracetam: these racetams enhance cognitive functions and as well improve your creative potential.
- Modafinil: this nootropic can really make you think out of the box! But be aware: it’s very intense so we recommend beginners not to use it.
Perfect Nootropic Stack For Mood Improvement
- Ashwagandha – a well-known herbal nootropic, that is used in traditional Indian medicine – Ayuverda. It is very effective in treating symptoms of anxiety and depression. It reduces the levels of the stress hormone called cortisol which helps relieve depression and anxiety. It’s a well-tested nootropic that rarely cause side-effects.
- Tianeptine – this nootropic can help you fighting with anxiety and will boost your mood. But it is a prescription one, keep that in mind. We strongly recommend to consult a doctor before taking it because it’s a powerful one.
- Noopept
- Inositol
- Aniracetam and others.
Perfect Nootropics Stack For Energy
- L-theanine + Carnitine (Acetyl L-Carnitine (ALCAR)): surely these are the most popular energetics among nootropics. This stack can boost your focus and recharge your batteries. As well, it is easy to use and available in all health shops.
- Coluracetam: is one from the racetams group. Working as a stimulant, it can boost your energy on a new level.
- NADH (Nicotinamide Adenine Dinucleotide + Hydrogen, or coenzyme 1): is a coenzyme that boosts alertness, mental performance, energy and memory.
- Rhodiola Rosea: is a herbal nootropic providing energy and cognition enhancement and improving your mood.
Perfect Nootropic Stack For Memory and Learning Ability
- L-theanine (for energy)
- Ginko Biloba (for improving memorizing and learning abilities).
- 10 mg Vinpocetine
- 200 mcg Huperzine A
- Alpha GPC
- Noopept
- Modafinil
- Racetams: Pramiracetam, Oxiracetam, Aniracetam
- Citicolin and others.
Perfect Nootropic Stack For Better Focus and Concentration
- Lion’s Mane Mashroom
- Alpha GPC
- Huprezine A
- Aniracetam (or other Racetams such as: piracetam, oxiracetam or pramiracetam)
- Fish oil (Omega 3)
- Bacopa Monnieri and others
- Rhodiola Rosea.
Perfect Nootropic Stack For Longevity, Thriving and Anti-aging
- Omega 3 = Uridine: this stack protect neuron cell membranes
- Coenzyme Q10: helps cells to recover
- Zync: regulates synaptic function of neurons
- Alpha GPC: provides various effects, as well as neural protection
- Carnitine (Acetyl L-Carnitine (ALCAR): reduces brain neurons death
- Quercetin – a great natural antioxidant found in apples and onions.
Perfect Nootropic Stack: What Mistakes To Avoid
When getting started towards creating your own nootropic stack, there are a few key mistakes you should try to avoid.
Nootropics can take 2 or more weeks to begin delivering results. So be patient. Too many people forget this and stop taking their nootropics after a few days without any noticeable improvement. This is a mistake that comes from inexperience.
Most nootropics optimise brain function through natural processes rather than directly stimulate certain pathways (some do). For this reason, we need to wait for new neurons to be constructed, blood flow to be improved, or nutritional deficiencies to be addressed and corrected.
None of this happens overnight. Most nootropics will take at least 2 weeks before their effects become truly noticeable.
Many people hear the word synergy and they think it’s always a good thing. This isn’t the case. Antagonistic synergy is what happens when two or more nootropics cancel each others effects out. This can be good in some cases, but in many cases it essentially neuters your expensive nootropic stack.
Antagonistic synergy is common when using nootropics with opposite effect profiles, such as a stimulant in combination with a sedative.
Generally speaking, it’s best to have a clear goal of what you want from your nootropic stack. Are you looking for help getting to sleep? Leave the stimulants out. Are you looking to use your stack to increase energy during the day? Leave sedatives out.
Other combinations of antagonistic synergy can include absorption interactions, such as with zinc and magnesium. These minerals use the same pathway for absorption in the gastrointestinal tract so taking them together makes both of them less bioavailable.
A good nootropic stack will spread these two out, OR combine them with something like vitamin B5 and piperine to increase their absorption.
Overkill nootropics are a very common mistake. People will hear about the acetylcholine boosting benefits of aniracetam, piracetam, and Noopept and think that if they mix them together they can get amazing results.
The truth is that this can be dangerous (see serotonin syndrome). Other times this is simply in effective and the addition of other (expensive) compounds are essentially doing nothing. More of one action doesn’t always mean more effect. We still rely on other processes to keep up with these processes.
Racetams for example increase choline uptake into the neurons. This will have little effect when there isn’t enough choline around the neurons for this to happen. This is why it’s wiser to stack a choline uptake enhancer like Aniracetam with a choline source like alpha-GPC instead.
A lot of novices forget about the existence of cofactors in their nootropic stacks. These compounds (such as B vitamins, and minerals) are necessary for the vast majority of cellular processes in the body.
When it comes to nootropics, we’re relying on these cellular processes to function as optimally as possible. When they’re deficient, it becomes a rate-limiting step in the process, which effectively reduces the potency of our nootropics.
Whenever taking nootropics with a specific goal in mind, such as increasing neurotransmitters, it’s important to consider what cofactors are involved with this process, and adding a few of these in with our stack to avoid wasting our nootropic stacks potential.
It’s important to stop all nootropics use from time to time. This is true with any supplement, as they can sometimes build in concentration in our bloodstream as a result of longer half-lives, or issues with our liver metabolism pathways.
Some people schedule cycles involving 3 weeks on, 1 off, or 3 days on 1 off. Another popular schedule is 3 months on, 1 weeks off. This really depends on your own preference.
This unique nootropic increases mental energy and improves cognitive function while lowering levels of anxiety and stress. It promotes a relaxing and energizing effect thus increasing your productivity. It is an exemplary supplement for people who need to think clearly and quickly in stressful situations and for students who are studying for exams. Picamilon is one of the best nootropics for social anxiety, it provides both energizing and calming effects. As well this nootropic for anxiety can lower blood pressure and harmonize sleep. The average daily dosage is between 50 to 400 mg. Picamilon is considered to be a safe supplement but still some side-effects can appear. One of the most common one is a low blood pressure and headaches. Rarely some allergic reactions can appear.
Titrating doses is very important. Too many novice nootropic users come in strong with the full dose on day one, only to experience side effects and quit taking nootropics altogether.
Titrating involves starting with small doses, and building up slowly over time to larger doses. This is especially important with the stronger classes of nootropics like the AMPAkines and stimulants.
It’s good practice to make changes to your stack. It allows you to experiment with new combinations and new nootropics to find out what works best for you. A common mistake people often make is changing too much too fast.
If you were taking a stack for several weeks and changed the whole stack suddenly, you won’t make any improvements. This is because you will have no way of knowing what changes made the sack better or worse.
It’s much wiser to make these changes slowly and one at a time. This way you can assess the changes of the stack, and dial it in over time.
This is a practice many experienced nootropic users do on a constant basis, changing the doses slightly one month, or swapping a compound another. They rarely do both at the same time.
This is very important to keep in mind. Nootropics fundamentally interact with brain function, which means that any other drug that affects brain function may have an interaction.
In some cases these interactions make the nootropic, the drug, or both ineffective. Other times, they potentiate each other (make each other stronger). This can be bad because it significantly increases the chances of developing side effects or causing harm elsewhere in the body.
The other thing to keep in mind when taking drugs is how they are processed in the liver. The liver uses a set of enzymes known as the P450 isoenzymes. There are many different groups of these isoenzymes used to metabolise different types of chemicals which have numerical names like 2D6 or 3A4.
If a drug and a nootropic are processed using this same system, it can slow down the metabolism of both, increasing the half life, and making it more likely for the drugs to build over time to toxic levels within the body.
If you are taking a drug, whether an antibiotic, antidepressant, or pain killer, it’s crucial that you research any possible interactions between the two. From this information you can decide if its a good idea to avoid that nootropic altogether, or if lowering the dose is going to be safe enough to avoid side effects.
Conclusion
Nootropics are usually can be blended and combines into different stacks. These make them more powerful and effective and can help you achieve several goals at a time.